➤➤➤RIBOSOMES➤➤➤
➤DISCOVERED BY;
★IN 1955, GEORGE EMIL PALADE WAS THE FIRST PERSON WHO STUDY THE
RIBOSOME, USING ELECTRON MICROSCOPE.
➤DEFINITION;
★CELL CONTAINS MANY TINY GRANULAR STRUCTURES KNOWN AS
"RIBOSOMES."
➤EUKARYOTIC RIBOSOME;
★EUKARYOTIC RIBOSOMES ARE COMPOSED OF AN ALMOST EQUAL
AMOUNT OF RNA AND PROTEIN,
HENCE THEY ARE RIBONUCLEOPROTEINS PARTICLES.
➤RIBOSOMAL RNA; (rRNA)
★THE RNA PRESENT IN RIBOSOME IS CALLED RIBOSOMAL RNA.
➤FORMS OF RIBOSOME;
★RIBOSOMES EXIST IN TWO FORMS;
"EITHER FREELY DISPERSED IN CYTOPLASM OR ATTACHED WITH RER AS TINY
GRANULES."
➤SUBUNITS;
★EACH EUKARYOTIC RIBOSOME CONSISTS OF TWO SUB-UNITS.
LARGER SUBUNIT;
★THE LARGER SUBUNIT SEDIMENTS AT 60S.
(S=SVEDBERG UNIT USED IN ULTRACENTRIFUGATION).
SMALLER SUBUNIT;
★WHILE SMALLER SUBUNIT SEDIMENTS AT 40S.
THE RIBOSOMES ARE ATTACHED TO MESSENGER RNA THROUGH SMALL
RIBOSOMAL SUBUNIT.
FORMATION OF 80S PARTICLE;
★TWO SUBUNITS ON ATTACHMENT WITH EACH OTHER FORM
80S PARTICLE.
➤CONTROLLED BY;
★THIS ATTACHMENT IS CONTROLLED BY THE PRESENCE OF
MG2+ IONS.
➤POLYSOME;
★A GROUP OF RIBOSOMES ATTACHED TO mRNA IS KNOWN AS POLYSOME.
➤ASSEMBLING OF NEW RIBOSOME;
★NEW RIBOSOMES ARE ASSEMBLED IN THE NUCLEOLUS OF THE NUCLEUS
FROM WHERE THEY ARE TRANSPORTED TO THE CYTOPLASM VIA THE
PORES IN NUCLEAR MEMBRANE.
➤FACTORY OF RIBOSOME;
★THE FACTORY OF RIBOSOME IS THE NUCLEOLUS, WHILE THAT OF
PROTEIN SYNTHESIS IS THE RIBOSOMES.
THE END
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